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Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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Cskは,抗原受容体媒介によるT系統細胞の発達と選択を制御する

C Schmedt1, K Saijo, T Niidome

  • 1Laboratory for Lymphocyte Signalling, University of Cologne, Germany. c.schmedt@uni-koeln.de

Nature
|September 11, 1998
PubMed
まとめ

乳頭細胞におけるカルボキシ末端Srcキナーゼ (Csk) の無活性化により,T細胞発育のためのT細胞前およびアルファベタT細胞受容体 (TCRs) の必要性が排除されます. これは,Cskskを明らかにします.

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