Smad3とSmad4は,c-Jun/c-Fosと協力して,TGF-β誘発の転写を媒介する

Y Zhang1, X H Feng, R Derynck

  • 1Department of Growth and Development, Program in Cell Biology, University of California at San Francisco, 94143-0640, USA.

Nature
|September 11, 1998
PubMed
まとめ

Smad3およびSmad4タンパク質は,AP1結合部位を通じて遺伝子転写を活性化し,SmadおよびAP-1因子と相互作用します. これは,SmadとMAPK/JNKの信号伝達経路の収束を示しています.

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