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Updated: Jul 22, 2026

In Vivo Biosensor Tracks Non-apoptotic Caspase Activity in Drosophila
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アダプタータンパク質Daxxによってアポトーシス信号調節キナーゼ1 (ASK1) の活性化

H Y Chang1, H Nishitoh, X Yang

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02138, USA.

Science (New York, N.Y.)
|September 22, 1998
PubMed
まとめ

Fas死亡受容体の経路は,Daxxタンパク質を通じたJun NH2端子キナーゼ (JNK) 信号伝達を活性化させ,DAXXタンパク質はASK1キナーゼと相互作用して活性化させ,アポトーシスを促進する.

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