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Updated: Jul 17, 2026

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry
14:47

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

Published on: May 17, 2016

皮膚炎特異的自己抗原Mi2は,ヒストン脱酸化酵素と核細胞の再構築活動を含む複合体の構成要素です

Y Zhang1, G LeRoy, H P Seelig

  • 1Howard Hughes Medical Institute, Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway 08854, USA.

Cell
|October 28, 1998
PubMed
まとめ

研究者らは,ヒストンの脱酸化とATPに依存した核細胞の再構築を結びつける新しいタンパク質複合体を発見した. Mi2βを含むこのクロマチンの改造複合体は,皮膚筋炎患者のがん転移に役割を果たすことを示唆しています.

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