関連する実験動画

Updated: Jul 20, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

カイナートとの複合体におけるグルタミン酸受容体リガンド結合核の構造

N Armstrong1, Y Sun, G Q Chen

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA.

Nature
|November 6, 1998
PubMed
まとめ

カイナートに結合するイオノトロプ的グルタミン酸受容体 (iGluRs) の結晶構造は,重要な相互作用を明らかにする. この発見は,受容体機能の理解を向上させ,神経学的疾患のための新しい治療用リガンドの設計に役立ちます.

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Ligand Binding Sites02:40

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Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
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