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Updated: Aug 18, 2026

Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b
10:20

Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b

Published on: November 11, 2016

InsP3受容体と貯蔵されたHtrp3チャンネルとの機能的相互作用

K Kiselyov1, X Xu, G Mozhayeva

  • 1Department of Physiology, University of Texas Southwestern Medical Center at Dallas, 75235, USA.

Nature
|December 16, 1998
PubMed
まとめ

貯蔵されたカルシウムチャネル (SOC) は,カルシウム (Ca2+) 貯蔵庫の枯渇によって活性化されます. この研究は,InsP3受容体がHtrp3 SOCと直接相互作用し,Ca2+の流入を調節し,細胞シグナル伝達におけるカップリング仮説を支持することを示しています.

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Single-Cell Calcium Imaging for Studying the Activation of Calcium Ion Channels07:17

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