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Updated: Jul 12, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

lin-35とlin-53は,C. elegansのRas経路を阻害する2つの遺伝子で,Rbに似たタンパク質と,その結合タンパク質RbAp48をコードする

X Lu1, H R Horvitz

  • 1Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA.

Cell
|January 6, 1999
PubMed
まとめ

合成マルチヴルヴァ (synMuv) 遺伝子は,C. elegansのヴァルヴァ誘導におけるRasシグナル伝達に敵対する. LIN-35 (Rb型) とLIN-53 (RbAp48型) は転写を抑制し,ヴァルバル細胞の運命遺伝子発現を防ぐ.

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Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans08:12

Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans

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CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.07:46

CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes.

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