全国コレステロール教育プログラム:進展と展望
1National Cholesterol Education Program, National Heart, Lung, and Blood Institute, Bethesda, MD 20892-2480, USA. cleemanj@gwgate.nhlbi.nih.gov
JAMA
|January 6, 1999
まとめ
国立コレステロール教育プログラム (NCEP) は,教育を通じて高血中コレステロールを成功裏に低下させました. 治療不足に対処するために,特に冠動脈疾患 (CHD) 患者において,継続的な努力が必要である.
科学分野:
- 心血管の健康について
- 公共衛生イニシアティブ 公共衛生イニシアティブ
- トランスレーションアル・リサーチ
背景:
- 国立心臓,肺,血液研究所 (NHLBI) は,50年間,研究翻訳を催化してきました.
- 国立コレステロール教育プログラム (NCEP) は,研究を実践に変換することで,この役割を例示しています.
- NCEPの成功は,科学的証拠と組織的なパートナーシップに基づいています.
研究 の 目的:
- NCEPの教育キャンペーンの影響を評価する.
- 高血圧コレステロールの流行を減らすための進展を評価する.
- コレステロール管理における残りの課題と将来の方向性を特定する.
主な方法:
- NCEPは,医療従事者や一般市民のための教育キャンペーンを利用した.
- プログラムの成功は,コレステロールの認識,食事習慣,血清コレステロール値,冠動脈疾患 (CHD) 死亡率の傾向を観察することによって測定されました.
- 分析は,1985年のNCEPの設立以来の期間に焦点を当てました.
主要な成果:
- 高い血中コレステロールの発生率を低減するうえで,過去10年間で顕著な進展がみられた.
- 主なトレンドには,コレステロールに対する意識の向上,食中の脂肪の摂取量の減少,血清コレステロールのレベルの低下,CHDの死亡率の低下が含まれています.
- 進歩にもかかわらず,コレステロールレベルは,特に既存のCHDの患者で,治療不足のままです.
結論:
- NCEPは,コレステロール管理に関する臨床および公衆衛生の実践を明らかに改善しました.
- 大規模な科学・教育的な課題が依然として存在し,継続的な努力が必要である.
- 将来のNCEP戦略は,CHD患者と初回予防の両方について,新興科学を活用します.
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