IL-2およびIFのガンマ媒介シグナル伝達におけるNmiとStat5およびStat1の機能的関連性

M Zhu1, S John, M Berg

  • 1Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1674, USA.

Cell
|February 16, 1999
PubMed
まとめ

核受容体相互作用タンパク質 (Nmi) は,コアクティベータータンパク質の募集を増加させることで,STAT媒介の転写を強化します. このタンパク質は,IL-2およびIFNgammaサイトカインに対する応答として転写を活性化します.

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