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NOS2 -/-受容者の弱体化された急性心臓拒絶は,アポトーシスの減少と相関しています

J Koglin1, D J Granville, T Glysing-Jensen

  • 1Cardiovascular Biology Laboratory, Harvard School of Public Health, Boston, Mass. 02115, USA.

Circulation
|February 17, 1999
PubMed
まとめ

酸化窒素合成酵素2 (NOS2) は,アポトーシスを誘導することによって,急性心臓アロ移植拒絶を促進します. NOS2のノックアウトマウスは,移植アポトーシスの減少と改善した結果を示し,NOS2が治療目標であることを示唆しています.

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