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rabindra.tharu.np@gmail.com
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Changing profile of lung cancer clinical characteristics in China: Over 8-year population-based study
BACKGROUND Although examinations and therapies for bronchial lung cancer, also called lung cancer (LC), have become more effective and precise, the morbidity and mortality of LC remain high worldwide. Describing the changing profile of LC characteristics over time is indispensable. This study aimed to understand the changes in real-world settings of LC and its characteristics…
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rabindra.tharu.np@gmail.com
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Light at night and lung cancer risk: A worldwide interdisciplinary and time-series study
BACKGROUND Light at night (LAN) has become a concern in interdisciplinary research in recent years. This global interdisciplinary study aimed to explore the exposure-lag-response association between LAN exposure and lung cancer incidence. METHODS LAN data were obtained from the Defense Meteorological Satellite Program’s Operational Linescan System. Data of lung cancer incidence, socio-demographic index, and smoking…
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rabindra.tharu.np@gmail.com
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Mechanisms of pulmonary endothelial barrier dysfunction in acute lung injury and acute respiratory distress syndrome
Endothelial cells (ECs) form a semi-permeable barrier between the interior space of blood vessels and the underlying tissues. Pulmonary endothelial barrier integrity is maintained through coordinated cellular processes involving receptors, signaling molecules, junctional complexes, and protein-regulated cytoskeletal reorganization. In acute lung injury (ALI) or its more severe form acute respiratory distress syndrome (ARDS), the loss…
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rabindra.tharu.np@gmail.com
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Biomarkers in idiopathic pulmonary fibrosis: Current insight and future direction
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease with a dismal prognosis. Early diagnosis, accurate prognosis, and personalized therapeutic interventions are essential for improving patient outcomes. Biomarkers, as measurable indicators of biological processes or disease states, hold significant promise in IPF management. In recent years, there has been a growing interest…
