-
rabindra.tharu.np@gmail.com
·
Prevalence and incidence of uveitis in patients with spondyloarthritis: the impact of the biologics era. Data from International ASAS-COMOSPA Study
OBJECTIVES Uveitis is a common extra-musculoskeletal manifestation in Spondyloarthritis (SpA). The aim of this study was to analyze the prevalence of uveitis in SpA patients, its association with geographical areas and to determine whether its incidence was different before and after the biological era. METHODS ASAS-COMOSPA is a retrospective study that includes patients fulfilling ASAS…
-
rabindra.tharu.np@gmail.com
·
Exploring genetic and immune cell dynamics in systemic lupus erythematosus patients with Epstein-Barr virus infection via machine learning
OBJECTIVES Epstein-Barr Virus (EBV) is a widespread virus implicated in various diseases, including Systemic Lupus Erythematosus (SLE). However, the specific genes and pathways altered in SLE patients with EBV infection remain unclear. We aimed to identify key genes and immune cells in SLE patients with EBV infection. METHODS The datasets of SLE (GSE50772 and GSE81622)…
-
rabindra.tharu.np@gmail.com
·
The 2024 British Society for Rheumatology guideline for management of systemic sclerosis
This guideline was developed according to the British Society for Rheumatology Guidelines Protocol by a Guideline Development Group comprising healthcare professionals with expertise in SSc and people with lived experience, as well as patient organization representatives. It is an update of the previous 2015 SSc guideline. The recommendations were developed and agreed by the group…
-
rabindra.tharu.np@gmail.com
·
Distinct clinical trajectories of gastrointestinal progression among patients with systemic sclerosis
OBJECTIVES Systemic sclerosis (SSc) is heterogeneous in its clinical presentation. Common manifestations cluster together, defining unique subgroups. This investigation aims to characterize gastrointestinal (GI) phenotypes and determine whether they can be distinguished by temporal progression. METHODS We examine a well-established SSc patient cohort with a modified Medsger GI severity score measured over time to determine…
