Pathology (excl. oral pathology) research. Pathology (excluding oral pathology) is the scientific study of disease processes in tissues, organs, and bodily fluids, essential for diagnosing and understanding a wide range of medical conditions within clinical sciences. This field encompasses diverse research areas, from molecular mechanisms to clinical diagnostics, providing critical insights into disease causes and progression. JoVE Visualize enhances access to this research by pairing PubMed articles with high-quality experiment videos, helping researchers and students gain a clearer understanding of study methods and findings.
Key Methods & Emerging Trends
Established Methods in Pathology
Core techniques in pathology include histopathology, immunohistochemistry, and cytology, which remain fundamental for analyzing tissue structure, cellular morphology, and protein expression patterns. Molecular diagnostics such as PCR and in situ hybridization are also widely used to identify genetic mutations and infectious agents. These well-established methods provide reliable and detailed information that supports diagnosis and informs therapeutic decisions across clinical sciences.
Innovative and Emerging Approaches
Emerging techniques in pathology increasingly leverage digital pathology and artificial intelligence to enhance diagnostic accuracy and workflow efficiency. Advances in multiplex imaging, single-cell sequencing, and spatial transcriptomics offer unprecedented resolution in understanding disease heterogeneity at a molecular level. These innovative tools are shaping the future of pathology research, allowing for more precise characterization of disease states and personalized treatment strategies.