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What is JoVE Visualize?

  1. Home
  3. Research Domains
  • Biomedical And Clinical Sciences
  • Pharmacology And Pharmaceutical Sciences
  • Clinical Pharmacology And Therapeutics

    • Clinical pharmacology and therapeutics

    AI-categorized content indicator

    Clinical pharmacology and therapeutics research is a multidisciplinary field dedicated to understanding how drugs interact with the human body to maximize therapeutic benefit while minimizing risk. This research area plays a crucial role within Pharmacology and pharmaceutical sciences by informing drug development, personalized medicine, and clinical treatment strategies. JoVE Visualize enhances this knowledge by pairing PubMed articles with JoVE’s experiment videos, offering researchers and students a comprehensive view of experimental procedures and scientific findings.

    Key Methods & Emerging Trends

    Core Methods in Clinical Pharmacology and Therapeutics

    Established methods in clinical pharmacology often include pharmacokinetic and pharmacodynamic studies, which analyze how drugs are absorbed, distributed, metabolized, and excreted, alongside their physiological effects. Clinical trials remain a cornerstone for evaluating drug efficacy and safety in diverse patient populations. Additionally, therapeutic drug monitoring and biomarker analysis contribute to optimizing dosage and treatment outcomes. These approaches collectively enable a structured understanding of drug behavior in clinical settings, supporting evidence-based practice and regulatory decisions.

    Emerging and Innovative Approaches

    Recent advances in clinical pharmacology and therapeutics leverage technologies such as high-throughput genomics and metabolomics to personalize drug therapy according to an individual’s genetic profile. The integration of real-world data and machine learning algorithms is shaping predictive modeling to assess drug responses and adverse effects more accurately. Innovations in microdosing and novel trial designs, including adaptive clinical trials, are enhancing drug development efficiency. JoVE Visualize supports exploring these pioneering methodologies alongside detailed experiment videos that illuminate cutting-edge research techniques.

    Recently Published Articles

    |May 21, 2026

    Dentinal tubule penetration of sodium hypochlorite and super-oxidized water using diode laser and passive ultrasonic activation: an in vitro confocal laser scanning microscopy study

    Palak Hirani, Manoj Chandak, Aditya Singh Patel, Anuja Ikhar, Shweta Sedani, Lalit Pawar

    |May 21, 2026

    Impact of Maternal Dental Anxiety on Oral Health-Related Quality of Life of Three-to-Six-Year-Old Children: A Cross-Sectional Study

    Sayali Pate, Mansi Mangela, Amar N Katre

    |May 21, 2026

    Effect of antioxidant solutions on the prevention and elimination of para-chloroaniline in root canals: an in vitro study

    Sidnei Flores de Pellegrin, Yasmin Padoin, Dylan Mehler Hoffmann, Iuri Robert Cardoso Bern, Renato Zanella, Guilherme Pauletto, Carlos Alexandre Souza Bier

    |May 21, 2026

    Genetic Identification of Potential Drug Targets for Dental Caries: A Mendelian Randomization Study

    Junlei Bi, Anqi Liu, Na Zhang, Yuxin Chen, Changqing Liu, Yongna Zhu, Hebao Wen, Caiyun Ma

    |May 21, 2026

    Mechanisms of TRIM21-mediated RUNX2 degradation via chaperone-mediated autophagy in periodontitis

    Yi Zhao, Yuyu Ge, Qiaoli Zhai, Zhiqiang Wang

    |May 21, 2026

    Efficacy and Safety of SPH3127 Tablet, a Novel Direct Renin Inhibitor, in Patients with Mild-to-Moderate Essential Hypertension: A Phase III Randomised Trial

    Qiang Lv, Changsheng Ma, Fang Wang, Lipeng Li, Gang Xiong, Zhanquan Li, Yanling Qu, Wenyue Pang, Wenliang Xiao, Hongyun Ruan, Liping Wei, Gang Liu, Jun Zhang, Qiong Liu, Ling Lin, Mingzhi Long, Huanming Li, Hong Yuan, Ling Liu, Yue Gao, Peijing Liu, Cuntai Zhang, Zhirong Wang, Jianhong Xie, Jiguang Wang, Xin Zhang, Yongyi Lu, Kai Huang, Min Liu, Jiyan Chen, Xiaohong Gao, Dongfang Wang, Xueping Ma, Xiaoping Chen, Yuhui Li, Yue Zhang, Xiangqing Kong, Fang Chen, Xiaowei Zhang, Jie Qi, Yuanyuan Cao, Yaohua Huang, Yue Zhang, Weiwei Cui

    |May 21, 2026

    Molecular insights into Profilin1-dependent regulation of cellular phosphatidylinositol-(4,5)-bisphosphate

    Andrew Orenberg, Michael Chirumbolo, Ian Eder, Jia-Jun Liu, Silvia Liu, David Gau, Yubo Tang, Klemens Rottner, Jianhua Luo, Gerald V Hammond, Partha Roy

    |May 21, 2026

    Eating and Swallowing Issues in Students Enrolled in Special Education Schools for Intellectual Disabilities

    Rena Hidaka, Ayako Nakane, Kazuharu Nakagawa, Haruka Tohara, Yuko Uchiyama, Shinya Wada, Chiyoko Hakuta, Koichiro Matsuo

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