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lowering-trials-in-the-elderly-and-a-look-to-the-future2026-08-26T12:28:23+00:00https://visualize.jove.com/11416577-apoptosis-in-cardiovascular-aging-research-future-directions2026-08-26T12:28:23+00:00https://visualize.jove.com/11416862-dna-methylation-variation-in-cloned-mice2026-08-26T12:28:23+00:00https://visualize.jove.com/11417479-high-level-resistance-to-glucocorticoids-associated-with-a-dysfunctional-glucocorticoid-receptor-in-childhood-acute-lymphoblastic-leukemia-cells-selected-for-methotrexate-resistance2026-08-26T12:28:23+00:00https://visualize.jove.com/11417628-occurrence-of-14-dioxane-in-cosmetic-raw-materials-and-finished-cosmetic-products2026-08-26T12:28:23+00:00https://visualize.jove.com/11417746-bone-metastasis-model-with-multiorgan-dissemination-of-human-small-cell-lung-cancer-sbc-5-cells-in-natural-killer-cell-depleted-scid-mice2026-08-26T12:28:23+00:00https://visualize.jove.com/11417748-differences-in-the-induction-of-dna-damage-cell-cycle-arrest-and-cell-death-by-5-fluorouracil-and-antifolates2026-08-26T12:28:23+00:00https://visualize.jove.com/11417992-male-breast-neoplasia-in-association-with-selective-serotonin-re-uptake-inhibitor-therapy-a-report-of-three-cases2026-08-26T12:28:23+00:00https://visualize.jove.com/11418001-dysfunction-of-stat4-leads-to-accelerated-incidence-of-chemical-induced-thymic-lymphomas-in-mice2026-08-26T12:28:23+00:00https://visualize.jove.com/11418017-role-of-prostanoids-and-endothelins-in-the-prevention-of-cyclosporine-induced-nephrotoxicity2026-08-26T12:28:23+00:00https://visualize.jove.com/11418101-expanding-coincident-signaling-by-pten-through-its-inositol-13456-pentakisphosphate-3-phosphatase-activity2026-08-26T12:28:23+00:00https://visualize.jove.com/11418133-differential-regulation-of-apoptosis-in-ak-5-tumor-cells-by-the-proto-oncogene-bcl-2-presence-of-bcl-2-dependent-and-independent-pathways2026-08-26T12:28:23+00:00https://visualize.jove.com/11418135-differential-regulation-of-cell-migration-and-cell-cycle-progression-by-fak-complexes-with-src-pi3k-grb7-and-grb2-in-focal-contacts2026-08-26T12:28:23+00:00https://visualize.jove.com/11418138-prb-suppresses-camptothecin-induced-apoptosis-in-human-osteosarcoma-saos-2-cells-by-inhibiting-c-jun-n-terminal-kinase2026-08-26T12:28:23+00:00https://visualize.jove.com/11418282-the-camp-dependent-protein-kinase-substrate-rap1-in-platelets-from-patients-with-obsessive-compulsive-disorder-or-schizophrenia2026-08-26T12:28:23+00:00https://visualize.jove.com/11418305-molecular-targeting-of-malignant-gliomas-with-novel-multiply-mutated-interleukin-13-based-cytotoxins2026-08-26T12:28:23+00:00https://visualize.jove.com/11418306-the-use-of-shiga-like-toxin-1-in-cancer-therapy2026-08-26T12:28:23+00:00https://visualize.jove.com/11418313-antiangiogenic-agents-and-their-promising-potential-in-combined-therapy2026-08-26T12:28:23+00:00https://visualize.jove.com/11418318-humoral-mechanisms-in-prostate-cancer-a-role-for-fsh2026-08-26T12:28:23+00:00https://visualize.jove.com/11418320-phase-ii-evaluation-of-suramin-in-advanced-renal-cell-carcinoma-a-southwest-oncology-group-study2026-08-26T12:28:23+00:00https://visualize.jove.com/11418477-rapamycin-induces-apoptosis-in-monocyte-and-cd34-derived-dendritic-cells-but-not-in-monocytes-and-macrophages2026-08-26T12:28:23+00:00https://visualize.jove.com/11418575-multiple-domains-are-required-for-the-toxic-activity-of-pseudomonas-aeruginosa-exou2026-08-26T12:28:23+00:00https://visualize.jove.com/11418587-impaired-synergistic-activation-of-stress-activated-protein-kinase-sapkjnk-in-mouse-embryonic-stem-cells-lacking-sek1mkk4-different-contribution-of-sek2mkk7-isoforms-to-the-synergistic-activation2026-08-26T12:28:23+00:00https://visualize.jove.com/11418594-the-p42p44-mitogen-activated-protein-kinase-activation-triggers-p27kip1-degradation-independently-of-cdk2cyclin-e-in-nih-3t3-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11418595-e2f-transcriptional-activation-requires-trrap-and-gcn5-cofactors2026-08-26T12:28:23+00:00https://visualize.jove.com/11418611-rgs2-promotes-adipocyte-differentiation-in-the-presence-of-ligand-for-peroxisome-proliferator-activated-receptor-gamma2026-08-26T12:28:23+00:00https://visualize.jove.com/11418634-nitric-oxide-inhibits-the-transcription-repressor-yin-yang-1-binding-activity-at-the-silencer-region-of-the-fas-promoter-a-pivotal-role-for-nitric-oxide-in-the-up-regulation-of-fas-gene-expression-in-human-tumor-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11418670-a-distinct-pathway-of-cell-mediated-apoptosis-initiated-by-granulysin2026-08-26T12:28:23+00:00https://visualize.jove.com/11418679-role-of-effector-cell-derived-il-4-il-5-and-perforin-in-early-and-late-stages-of-type-2-cd8-effector-cell-mediated-tumor-rejection2026-08-26T12:28:23+00:00https://visualize.jove.com/11418680-induction-of-apoptosis-in-human-t-cells-by-actinobacillus-actinomycetemcomitans-cytolethal-distending-toxin-is-a-consequence-of-g2-arrest-of-the-cell-cycle2026-08-26T1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rotein-kinase-phosphorylates-and-targets-inducible-camp-early-repressor-to-ubiquitin-mediated-destruction2026-08-26T12:28:23+00:00https://visualize.jove.com/11466328-unexpected-transcriptional-induction-of-monocyte-chemoattractant-protein-1-by-proteasome-inhibition-involvement-of-the-c-jun-n-terminal-kinase-activator-protein-1-pathway2026-08-26T12:28:23+00:00https://visualize.jove.com/11466377-dna-fusion-vaccine-designed-to-induce-cytotoxic-t-cell-responses-against-defined-peptide-motifs-implications-for-cancer-vaccines2026-08-26T12:28:23+00:00https://visualize.jove.com/11466378-virally-infected-hepatocytes-are-resistant-to-perforin-dependent-ctl-effector-mechanisms2026-08-26T12:28:23+00:00https://visualize.jove.com/11466405-cross-presentation-by-dendritic-cells-of-tumor-antigen-expressed-in-apoptotic-recombinant-canarypox-virus-infected-dendritic-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11466560-angiotensin-ii-induces-p27kip1-expression-in-renal-tubules-in-vivo-role-of-reactive-oxygen-species2026-08-26T12:28:23+00:00https://visualize.jove.com/11466609-spontaneously-immortalized-cell-lines-obtained-from-adult-atm-null-mice-retain-sensitivity-to-ionizing-radiation-and-exhibit-a-mutational-pattern-suggestive-of-oxidative-stress2026-08-26T12:28:23+00:00https://visualize.jove.com/11466611-the-adenine-nucleotide-translocator-a-target-of-nitric-oxide-peroxynitrite-and-4-hydroxynonenal2026-08-26T12:28:23+00:00https://visualize.jove.com/11466615-healthy-mice-with-an-altered-c-myc-gene-role-of-the-3-untranslated-region-revisited2026-08-26T12:28:23+00:00https://visualize.jove.com/11466619-activation-of-the-p21cip1waf1-promoter-by-bone-morphogenetic-protein-2-in-mouse-b-lineage-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11466620-cdc25b-activity-is-regulated-by-14-3-32026-08-26T12:28:23+00:00https://visualize.jove.com/11466625-oncogenic-transformation-induced-by-membrane-targeted-akt2-and-akt32026-08-26T12:28:23+00:00https://visualize.jove.com/11466694-association-of-p53-gene-mutations-with-sensitivity-to-tzt-1027-in-patients-with-clinical-lung-and-renal-carcinoma2026-08-26T12:28:23+00:00https://visualize.jove.com/11466981-new-basis-for-development-of-anticancer-drugs2026-08-26T12:28:23+00:00https://visualize.jove.com/11467078-current-status-of-the-cytosolic-sulfotransferases-in-the-metabolic-activation-of-promutagens-and-procarcinogens2026-08-26T12:28:23+00:00https://visualize.jove.com/11467357-inhibition-of-cellular-proliferation-by-drug-targeting-of-cyclin-dependent-kinases2026-08-26T12:28:23+00:00https://visualize.jove.com/11467412-streptozotocin-and-alloxan-based-selection-improves-toxin-resistance-of-insulin-producing-rinm-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11467419-defective-morphogenesis-and-functional-maturation-in-fetal-islet-like-cell-clusters-from-oletf-rat-a-model-of-niddm2026-08-26T12:28:23+00:00https://visualize.jove.com/11467446-the-ras-signaling-pathway-in-mammary-tumorigenesis-and-metastasis2026-08-26T12:28:23+00:00https://visualize.jove.com/11467450-notch-signaling-in-mammary-gland-tumorigenesis2026-08-26T12:28:23+00:00https://visualize.jove.com/11467453-tgf-beta-signaling-in-mammary-gland-development-and-tumorigenesis2026-08-26T12:28:23+00:00https://visualize.jove.com/11467454-regulation-of-mouse-mammary-gland-development-and-tumorigenesis-by-the-erbb-signaling-network2026-08-26T12:28:23+00:00https://visualize.jove.com/11467455-phosphatidylinositol-3-kinase-signaling-in-mammary-tumorigenesis2026-08-26T12:28:23+00:00https://visualize.jove.com/11467743-histone-modifications-and-apoptosis-cause-or-consequence2026-08-26T12:28:23+00:00https://visualize.jove.com/11467831-inhibition-of-chok-is-an-efficient-antitumor-strategy-for-harvey-kirsten-and-n-ras-transformed-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11467861-dissociation-of-5-amp-activated-protein-kinase-activation-and-glucose-uptake-stimulation-by-mitochondrial-uncoupling-and-hyperosmolar-stress-differential-sensitivities-to-intracellular-ca2-and-protein-kinase-c-inhibition2026-08-26T12:28:23+00:00https://visualize.jove.com/11468209-pioglitazone-enhances-cytokine-induced-apoptosis-in-vascular-smooth-muscle-cells-and-reduces-intimal-hyperplasia2026-08-26T12:28:23+00:00https://visualize.jove.com/11468212-pathological-analysis-of-local-delivery-of-paclitaxel-via-a-polymer-coated-stent2026-08-26T12:28:23+00:00https://visualize.jove.com/11468275-temporal-and-spatial-expression-patterns-of-the-crx-transcription-factor-and-its-downstream-targets-critical-differences-during-human-and-mouse-eye-development2026-08-26T12:28:23+00:00https://visualize.jove.com/11468406-crystallization-and-preliminary-crystallographic-studies-of-an-apoptosis-linked-calcium-binding-protein-alg-22026-08-26T12:28:23+00:00https://visualize.jove.com/11468778-cigarette-smoking-and-aneuploidy-in-human-sperm2026-08-26T12:28:23+00:00https://visualize.jove.com/11468974-characterization-of-dna-protein-cross-links-forming-un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otypic-differentiation-or-apoptosis-in-a-dose-dependent-fashion-involvement-of-the-dopamine-transporter-and-p532026-08-26T12:28:23+00:00https://visualize.jove.com/11872954-oligonucleotide-fishing-for-stat6-cross-talk-between-il-4-and-chemokines2026-08-26T12:28:23+00:00https://visualize.jove.com/11873239-effects-of-interleukin-2-therapy-on-lymphocyte-magnesium-levels2026-08-26T12:28:23+00:00https://visualize.jove.com/11873517-development-of-chemopreventive-strategies-for-radiation-induced-cancer-targeting-radiation-induced-genetic-alterations2026-08-26T12:28:23+00:00https://visualize.jove.com/11873574-tyrosine-kinase-receptor-ras-erk-signal-transduction-pathway-as-therapeutic-tarfet-in-cancer2026-08-26T12:28:23+00:00https://visualize.jove.com/11873606-stereotactic-biopsy-of-polylmorphic-tumors-and-brain-tumors-invisible-in-ct-image2026-08-26T12:28:23+00:00https://visualize.jove.com/11873614-treatment-of-neurodegenerative-diseases-new-perspectives2026-08-26T12:28:23+00:00https://visualize.jove.com/11874241-regulation-of-fibroblast-growth-factor-2-and-fibroblast-growth-factor-receptors-by-transforming-growth-factor-beta-in-human-osteoblastic-mg-63-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11874446-effects-of-aminoguanidine-and-tolrestat-on-the-development-of-ocular-and-renal-structural-changes-in-experimental-diabetic-rats2026-08-26T12:28:23+00:00https://visualize.jove.com/11874485-halofuginone-an-inhibitor-of-type-i-collagen-synthesis-and-skin-sclerosis-blocks-transforming-growth-factor-beta-mediated-smad3-activation-in-fibroblasts2026-08-26T12:28:23+00:00https://visualize.jove.com/11874491-bcl-2-and-bcl-xl-antisense-oligonucleotides-induce-apoptosis-in-melanoma-cells-of-different-clinical-stages2026-08-26T12:28:23+00:00https://visualize.jove.com/11874581-dissociation-between-dialysis-adequacy-and-ktv2026-08-26T12:28:23+00:00https://visualize.jove.com/11874628-gene-therapy-of-murine-solid-tumors-with-t-cells-transduced-with-a-retroviral-vascular-endothelial-growth-factor-immunotoxin-target-gene2026-08-26T12:28:23+00:00https://visualize.jove.com/11874631-cell-specific-cre-mediated-activation-of-the-diphtheria-toxin-gene-in-pituitary-tumor-cells-potential-for-cytotoxic-gene-therapy2026-08-26T12:28:23+00:00https://visualize.jove.com/11874700-myometrial-expression-of-11-beta-hydroxysteroid-dehydrogenase-type-2-in-rat-pregnancy2026-08-26T12:28:23+00:00https://visualize.jove.com/11874717-expression-and-action-of-the-growth-hormone-releasing-peptide-ghrelin-and-its-receptor-in-prostate-cancer-cell-lines2026-08-26T12:28:23+00:00https://visualize.jove.com/11874944-differential-effects-of-metformin-and-troglitazone-on-cardiovascular-risk-factors-in-patients-with-type-2-diabetes2026-08-26T12:28:23+00:00https://visualize.jove.com/11874999-trail-and-its-receptors-in-the-colonic-epithelium-a-putative-role-in-the-defense-of-viral-infections2026-08-26T12:28:23+00:00https://visualize.jove.com/11875005-genetic-deficiency-in-the-chemokine-receptor-ccr1-protects-against-acute-clostridium-difficile-toxin-a-enteritis-in-mice2026-08-26T12:28:23+00:00https://visualize.jove.com/11875057-atm-mediates-phosphorylation-at-multiple-p53-sites-including-ser46-in-response-to-ionizing-radiation2026-08-26T12:28:23+00:00https://visualize.jove.com/11875067-rho-activity-can-alter-the-translation-of-p27-mrna-and-is-important-for-rasv12-induced-transformation-in-a-manner-dependent-on-p27-status2026-08-26T12:28:23+00:00https://visualize.jove.com/11875078-caspase-proteolysis-of-the-cohesin-component-rad21-promotes-apoptosis2026-08-26T12:28:23+00:00https://visualize.jove.com/11875109-induction-of-human-liver-x-receptor-alpha-gene-expression-via-an-autoregulatory-loop-mechanism2026-08-26T12:28:23+00:00https://visualize.jove.com/11875111-inhibition-of-androgen-receptor-ar-function-by-the-reproductive-orphan-nuclear-receptor-dax-12026-08-26T12:28:23+00:00https://visualize.jove.com/11875250-effect-of-treatment-with-different-doses-of-17-beta-estradiol-on-insulin-receptor-substrate-12026-08-26T12:28:23+00:00https://visualize.jove.com/11875426-tumor-antigen-specific-induction-of-transcriptionally-targeted-retroviral-vectors-from-chimeric-immune-receptor-modified-t-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11875497-cloned-mice-have-an-obese-phenotype-not-transmitted-to-their-offspring2026-08-26T12:28:23+00:00https://visualize.jove.com/11875499-tumor-cell-resistance-to-death-receptor-induced-apoptosis-through-mutational-inactivation-of-the-proapoptotic-bcl-2-homolog-bax2026-08-26T12:28:23+00:00https://visualize.jove.com/11875500-restoration-of-the-tumor-suppressor-function-to-mutant-p53-by-a-low-molecular-weight-compound2026-08-26T12:28:23+00:00https://visualize.jove.com/11875643-specific-inhibition-of-human-skin-fibroblast-chemotaxis-to-platelet-derived-growth-factor-a-chain-homodimer-by-transforming-growth-factor-beta12026-08-26T12:28:23+00:00https://visualize.jove.com/11875710-role-of-beta3-adrenergic-receptors-in-the-action-o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ells-in-vitro-revealed-by-the-comet-assay2026-08-26T12:28:23+00:00https://visualize.jove.com/11911272-induction-of-apoptotic-pathway-in-the-vestibule-of-cisplatin-cddp-treated-guinea-pigs2026-08-26T12:28:23+00:00https://visualize.jove.com/11911275-potential-of-the-proteasomal-inhibitor-mg-132-as-an-anticancer-agent-alone-and-in-combination2026-08-26T12:28:23+00:00https://visualize.jove.com/11911506-estrogen-receptor-downregulators-new-antihormonal-therapy-for-advanced-breast-cancer2026-08-26T12:28:23+00:00https://visualize.jove.com/11911802-the-proapoptotic-9-2-isozyme-of-2-5-a-synthetase-cannot-substitute-for-the-sperm-functions-of-the-proapoptotic-protein-bax2026-08-26T12:28:23+00:00https://visualize.jove.com/11911833-alterations-in-the-expression-of-cytochrome-c-oxidase-subunits-in-doxorubicin-resistant-leukemia-k562-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11911840-fascd95-mediated-apoptosis-in-human-glioblastoma-cells-a-target-for-sensitisation-to-topoisomerase-i-inhibitors2026-08-26T12:28:23+00:00https://visualize.jove.com/11911842-a-doxorubicin-cngrc-peptide-conjugate-with-prodrug-properties2026-08-26T12:28:23+00:00https://visualize.jove.com/11911945-radicicol-represses-the-transcriptional-function-of-the-estrogen-receptor-by-suppressing-the-stabilization-of-the-receptor-by-heat-shock-protein-902026-08-26T12:28:23+00:00https://visualize.jove.com/11911964-roscovitine-inhibits-ongoing-dna-synthesis-in-human-cervical-cancer2026-08-26T12:28:23+00:00https://visualize.jove.com/11911965-overexpression-of-cyclooxygenase-2-cox-2-in-human-primitive-neuroectodermal-tumors-effect-of-celecoxib-and-rofecoxib2026-08-26T12:28:23+00:00https://visualize.jove.com/11911966-antitumoral-effects-of-recombinant-adenovirus-ykl-1001-conditionally-replicating-in-alpha-fetoprotein-producing-human-liver-cancer-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11911970-molecular-and-immunohistochemical-analysis-of-signaling-adaptor-protein-crk-in-human-cancers2026-08-26T12:28:23+00:00https://visualize.jove.com/11912025-how-do-bacteria-resist-human-antimicrobial-peptides2026-08-26T12:28:23+00:00https://visualize.jove.com/11912058-effect-of-tributyltin-on-adenylate-content-and-enzyme-activities-of-teleost-sperm-a-biochemical-approach-to-study-the-mechanisms-of-toxicant-reduced-spermatozoa-motility2026-08-26T12:28:23+00:00https://visualize.jove.com/11912127-an-atm-independent-s-phase-checkpoint-response-involves-chk1-pathway2026-08-26T12:28:23+00:00https://visualize.jove.com/11912128-generation-of-effective-antitumor-vaccines-using-photodynamic-therapy2026-08-26T12:28:23+00:00https://visualize.jove.com/11912129-target-gene-mutation-profile-differs-between-gastrointestinal-and-endometrial-tumors-with-mismatch-repair-deficiency2026-08-26T12:28:23+00:00https://visualize.jove.com/11912137-significance-of-mad2-expression-to-mitotic-checkpoint-control-in-ovarian-cancer-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11912141-transcriptional-regulation-of-mitotic-genes-by-camptothecin-induced-dna-damage-microarray-analysis-of-dose-and-time-dependent-effects2026-08-26T12:28:23+00:00https://visualize.jove.com/11912142-oncolytic-reovirus-against-ovarian-and-colon-cancer2026-08-26T12:28:23+00:00https://visualize.jove.com/11912143-simultaneous-inhibition-of-the-receptor-kinase-activity-of-vascular-endothelial-fibroblast-and-platelet-derived-growth-factors-suppresses-tumor-growth-and-enhances-tumor-radiation-response2026-08-26T12:28:23+00:00https://visualize.jove.com/11912144-selective-sensitization-of-transformed-cells-to-flavopiridol-induced-apoptosis-following-recruitment-to-s-phase2026-08-26T12:28:23+00:00https://visualize.jove.com/11912153-in-lymphatic-cells-par-4-sensitizes-to-apoptosis-by-down-regulating-bcl-2-and-promoting-disruption-of-mitochondrial-membrane-potential-and-caspase-activation2026-08-26T12:28:23+00:00https://visualize.jove.com/11912154-adenovirus-mediated-e2f-1-gene-transfer-sensitizes-melanoma-cells-to-apoptosis-induced-by-topoisomerase-ii-inhibitors2026-08-26T12:28:23+00:00https://visualize.jove.com/11912160-atypical-protein-kinase-c-zeta-as-a-target-for-chemosensitization-of-tumor-cells2026-08-26T12:28:23+00:00https://visualize.jove.com/11912166-noninvasive-imaging-of-spontaneous-retinoblastoma-pathway-dependent-tumors-in-mice2026-08-26T12:28:23+00:00https://visualize.jove.com/11912168-dna-damage-is-able-to-induce-senescence-in-tumor-cells-in-vitro-and-in-vivo2026-08-26T12:28:23+00:00https://visualize.jove.com/11912174-prevention-of-irradiation-induced-glioma-cell-invasion-by-temozolomide-involves-caspase-3-activity-and-cleavage-of-focal-adhesion-kinase2026-08-26T12:28:23+00:00https://visualize.jove.com/11912191-the-molecular-basis-of-src-kinase-specificity-during-vertebrate-mesoderm-formation2026-08-26T12:28:23+00:00https://visualize.jove.com/11912200-regulatory-role-for-src-and-phosphatidylinositol-3-kinase-in-initiation-of-fibronectin-matrix-assembly2026-08-26T12:28:23+00:00https://vis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