控制对巴基斯坦儿童腹的影响:社区随机试验
D C Chavasse1, R P Shier, O A Murphy
1London School of Hygiene and Tropical Medicine, London, UK.
Lancet (London, England)
|February 19, 1999
概括
基于杀虫剂的防方法显著降低了发展中国家幼儿的腹疾病发病率. 这种控制策略显示出对公共卫生干预对腹疾病的承诺.
科学领域:
- 环境健康 环境健康
- 传染病流行病学 传染病流行病学
- 矢量控制控制器 矢量控制器
背景情况:
- 腹疾病每年导致数百万儿童死亡,需要发展中国家制定有效的预防策略.
- 被怀疑是腹疾病的载体,但缺乏关于控制影响的强有力的证据.
- 这项研究研究了喷杀虫剂对发展中国家腹发病率的影响.
研究的目的:
- 评估基于杀虫剂的控制对五岁以下儿童腹发病率的影响.
- 为了比较杀虫剂喷与没有干预在减少腹疾病的有效性.
- 评估诱的陷作为补充控制方法的有效性.
主要方法:
- 一项涉及六个村庄的随机研究,在特定的季节在治疗组中用于控制的杀虫剂.
- 在五岁以下的儿童中,每周通过母亲报告监测腹发作.
- 在哨兵化合物中使用粘性纸来评估密度.
主要成果:
- 在1995年和1996年的目标季节,喷杀虫剂有效地消除了.
- 在被喷的村庄中,腹发病率在季期间与对照村庄相比下降了23% (p=0.007).
- 在飞季之外没有观察到腹发病率的显著差异;诱陷被证明是无效的.
结论:
- 使用杀虫剂喷来控制,可以大大减少发展中国家的腹发病率.
- 这项干预的影响与当前世界卫生组织推的腹疾病控制计划相似或更大.
- 进一步研究和开发飞传播疾病传播中断技术至关重要.
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