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Updated: Jul 21, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
07:49

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Published on: August 3, 2018

通过干扰素-马/STAT通路抑制转化生长因子-β/SMAD信号传递

L Ulloa1, J Doody, J Massagué

  • 1Cell Biology Program and Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

Nature
|March 6, 1999
PubMed
概括

干扰素- (IFN-) 通过诱导Smad7来抑制转化生长因子-β (TGF-β) 信号传递,从而阻断Smad3的激活. 这揭示了STAT和SMAD通路之间的交叉对话,解释了它们对抗性的细胞效应.

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