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Updated: Jul 15, 2026

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
06:43

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Published on: December 7, 2013

素-C在富含巨细胞的人类冠状动脉动脉样硬化斑块中表达

K Wallner1, C Li, P K Shah

  • 1Atherosclerosis Research Center, Divisions of Cardiology and Anatomic Pathology, Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Circulation
|March 17, 1999
PubMed
概括

动脉样硬化斑块中的特纳辛-C (TN-C) 表达与炎症和巨细胞有关,而不是斑块大小. 巨细胞是斑块矩阵重塑中的关键参与者.

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Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...