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Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
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双相冲击持续时间对不同电极配置和2相容量的除门的影响:通过上限脆弱性测定进行预测
P N Schauerte1, K Ziegert, M Waldmann
1University of Technology, Department of Cardiology and Cardiovascular Surgery, Aachen, Germany. Patrick-Schauerte@ouhsc.edu
Circulation
|March 23, 1999
概括
脆弱性的上限 (ULV) 可以预测除门 (DFT) 波形. 较低的2相电容降低了DFT,无论双相冲击持续时间 (BSD).
科学领域:
- 心血管生理学心血管生理学
- 电力生理学 电力生理学
- 医疗器械工程 医疗器械工程
背景情况:
- 除门 (DFT) 受双相冲击持续时间 (BSD),电极配置和电容的影响.
- 脆弱性的上限 (ULV) 可以作为DFT的估计.
研究的目的:
- 调查ULV是否可以预测具有最低DFT的波形.
- 评估不同配置和第二阶段容量的使用猪ULV对DFT预测的影响.
主要方法:
- 在18头猪中使用上下协议确定了10个BSD的DFT和ULV.
- 通过T波扫描测量ULVs 在心室节拍过程中.
- 使用了两个电极配置 (AC+SVC和AC) 和各种容量 (150μF和300μF).
主要成果:
- 在所有协议中,ULV和DFT显示出显著的线性相关性 (r=0.78到0.84).
- 观察到AC+SVC的最低DFT为10毫秒,AC的最低DFT为14毫秒.
- 降低2期电容降低了DFT,同时增加了最低DFT.
结论:
- 通过ULV测定,可以预测具有最低DFT的波形.
- 最低DFT的最佳BSD在AC+SVC和AC配置之间有所不同.
- 降低2期电容对于降低DFTs是有益的.
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