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Updated: May 4, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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控制酶诱导在骨髓性白血病细胞的分化中的控制

A Krystosek, L Sachs

    Cell
    |December 1, 1976
    PubMed
    概括

    研究人员使用小鼠骨髓性白血病细胞克隆开发了一种系统,用于研究细胞分化期间的酶合成. 他们发现,诱导Fc和C3受体之前的溶酶生产,揭示了骨髓发育中不同的控制机制.

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    Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
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