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Updated: Jul 12, 2026

Analysis of the c-KIT Ligand Promoter Using Chromatin Immunoprecipitation
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通过IKKbeta亚单元酸化,对IkappaB激酶活性进行正负调节

M Delhase1, M Hayakawa, Y Chen

  • 1Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0636, USA.

Science (New York, N.Y.)
|April 9, 1999
PubMed
概括

核因子kappaB (NF-kappaB) 激酶β (IKKbeta) 的抑制剂是由炎症信号激活的,与IKKalpha不同. 这种激活导致NF-kappaB信号传递,但随后的IKKbeta自酸化限制了炎症反应.

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