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Updated: Jul 13, 2026

Analysis of Protein Folding, Transport, and Degradation in Living Cells by Radioactive Pulse Chase
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Published on: February 12, 2019

在体外蛋白质折叠的演变

M H Cordes1, N P Walsh, C J McKnight

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Science (New York, N.Y.)
|April 9, 1999
PubMed
概括

蛋白质工程揭示了微小的突变可以显著改变蛋白质结构. 一个"交换机"突变的Arc抑制器证明,小的遗传变化可以导致新的蛋白质折叠,而没有广泛的突变发生.

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