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血糖指数作为血清高脂胆固醇度的决定因素
1Department of Nutrition and Dietetics, Hammersmith Hospitals NHS Trust, London, UK. gfrost@rpms.ac.uk
Lancet (London, England)
|April 13, 1999
概括
饮食葡萄糖指数显著影响高密度胆固醇水平. 高血糖指数饮食与较低的HDL胆固醇有关,这表明它在管理心脏健康方面的重要性.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 代谢健康 代谢健康
背景情况:
- 饮食显著影响冠心病 (CHD) 的患病率.
- 胰岛素敏感性和高密度胆固醇是心脏病的关键代谢预测因素,两者都受到饮食的影响.
- 高血糖指数的碳水化合物会增加食后葡萄糖和胰岛素,降低胰岛素敏感性,增加心脏病风险.
研究的目的:
- 为了研究饮食血糖指数和血清HDL胆固醇度之间的关系.
- 为了确定血糖指数是否是高密度胆固醇水平的重要决定因素.
主要方法:
- 从1986-87年英国成年人调查 (n=2200) 中重新分析了饮食,人体测量和生物化学数据.
- 使用多重回归模型来评估血清脂质度 (总胆固醇,高胆固醇,低胆固醇) 和饮食因素之间的关联.
- 检查了血糖指数,碳水化合物类型和脂肪摄入量作为饮食变量.
主要成果:
- 在男性和女性中,在血清高密度胆固醇和饮食葡萄糖指数之间观察到显著的负相关性.
- 这种关系在统计学上是显著的 (男性p=0.02,女性p<0.0001).
- 在饮食糖分指数和总或LDL胆固醇之间没有发现显著的关联,也没有发现与其他饮食成分的关联.
结论:
- 饮食葡萄糖指数是唯一与中年成人血清高密度胆固醇显著相关的饮食变量.
- 饮食的血糖指数是血清HDL胆固醇的更强有力的预测因素,而不是饮食脂肪摄入量.
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