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在患有脑缺血事件的患者中,心房隔膜动脉瘤的发生频率
Y Agmon1, B K Khandheria, I Meissner
1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
Circulation
|April 20, 1999
概括
耳前隔膜动脉瘤 (ASA) 在患有脑缺血事件的患者中比一般人群中更常见. 这一发现表明,通常与圆孔 (PFO) 相关的ASA可能是心血管栓塞的重要来源.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 血管医学 血管医学
背景情况:
- 前庭隔膜动脉瘤 (ASA) 是心血管栓塞的潜在危险因素.
- 在一般人群中ASA的患病率及其与大脑缺血事件的关联还不清楚.
研究的目的:
- 为了确定ASA在一般人群中的频率.
- 为了比较脑缺血事件患者与普通人群中的ASA频率.
主要方法:
- 使用基于人口的样本 (363名受试者) 来确定ASA频率.
- 在患有脑缺血事件的患者中 (355名受试者) 的ASA频率与对照人群进行了比较.
- 使用过食道心声学和对比注射.
主要成果:
- 一般人群中的ASA患病率为2.2%.
- 在7.9%的患有脑缺血事件的患者中发现了ASA,这是一个明显更高的频率 (OR,3.65;P=0.002).
- ASA与卵孔 (PFO) 有着强烈的关联 (OR, 4.57).
结论:
- 基于人口的ASA患病率为2.2%.
- 在经历脑缺血事件的患者中,ASA的发生频率明显高.
- 经常与PFO相关的ASA是这些患者可能的心血管栓塞源.
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