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Updated: Jul 17, 2026

Improved Method for the Preparation of a Human Cell-based, Contact Model of the Blood-Brain Barrier
08:40

Improved Method for the Preparation of a Human Cell-based, Contact Model of the Blood-Brain Barrier

Published on: November 13, 2013

通过人类重组组织等离子体激活剂进行非蛋白质神经保护

Y H Kim1, J H Park, S H Hong

  • 1National Creative Research Initiative Center for the Study of Central Nervous System Zinc and Department of Neurology, University of Ulsan College of Medicine, 388-1 Poongnap-Dong Songpa-Gu, Seoul 138-736, Korea.

Science (New York, N.Y.)
|April 24, 1999
PubMed
概括

组织等离子体激活剂 (tPA) 减少诱导的神经毒性,独立于其凝块溶解作用. 这一发现为tPA提供了新的见解.

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Clot Retraction and Fibrinolysis01:16

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After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.