维生素C摄入的标准和建议
M Levine1, S C Rumsey, R Daruwala
1Molecular and Clinical Nutrition Section, Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
JAMA
|April 27, 1999
概括
新的维生素C摄入建议建议每天摄入120毫克的建议饮食补贴 (RDA),其中5份水果和蔬菜提供足够的摄入量 (AI). 每天消费超过1克可能会给健康带来风险.
科学领域:
- 营养科学 营养科学
- 生物化学 生物化学
- 公共卫生 公共卫生
背景情况:
- 食品和营养委员会正在修订维生素C摄入量建议,更新了1989年60毫克的建议饮食补贴 (RDA).
- 来自生物化学,分子,流行病学和临床研究的大量新数据可供考虑.
- 修订过程考虑了九个关键标准,包括各种健康结果的饮食可用性,生物可用性和剂量反应关系.
研究的目的:
- 应用已确定的标准来制定新的维生素C的饮食参考摄入量 (DRI).
- 提出更新的参考值,包括估计平均需求 (EAR),RDA,充足摄入量 (AI) 和可容忍的上摄入量水平 (UL).
- 为医生和公众提供基于证据的指导,了解最佳的维生素C消费.
主要方法:
- 基于九个特定标准对现有科学数据的评估.
- 计算维生素C的估计平均需求 (EAR).
- 根据EAR和其他标准确定RDA,AI和可容忍的上摄入水平 (UL).
主要成果:
- 建议维生素C的EAR为100毫克/天,导致建议的RDA为120毫克/天.
- 充足摄入量 (AI) 设定为每天从5份水果和蔬菜中摄入200毫克,或每天100毫克以防止缺乏.
- 建议的可容忍上摄入水平 (UL) 是每天少于1克 (1000毫克) 的维生素C.
结论:
- 每天五份水果和蔬菜可以支持癌症预防和健康人群摄入足够的维生素C.
- 每天摄入1克或更多的维生素C可能会导致一些人的不良反应.
- 拟议的DRI提供了更新的,基于证据的维生素C营养指南.
相关概念视频
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Vitamins
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Dosage Regimen: Individualization
Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
Coronary Artery Disease IV: Preventive Measures
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...

