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相关概念视频

Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...

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相关实验视频

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Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

绝经后的美国女性患有急性关节骨折的隐性维生素D缺乏症

M S LeBoff1, L Kohlmeier, S Hurwitz

  • 1Department of Internal Medicine, Brigham and Women's Hospital, Boston, Mass 02115, USA. msleboff@bics.bwh.harvard.edu

JAMA
|May 5, 1999
PubMed
概括

绝经后患有部骨折的女性往往缺乏维生素D,甲状腺上腺激素水平高. 解决维生素D缺乏症可能有助于预防未来的骨折并改善愈合.

科学领域:

  • 内分泌学 在内分泌学.
  • 骨的新陈代谢 骨的新陈代谢
  • 老年医学 老年医学

背景情况:

  • 低维生素D水平与女性部骨折有关.
  • 关于美国女性急性关节骨折的维生素D状况的数据有限.

研究的目的:

  • 为了比较绝经后妇女的维生素D和副甲状腺激素水平,与那些接受选择性关节置换的女性相比.
  • 评估急性部骨折住院妇女的维生素D状况.

主要方法:

  • 一个比较的病例系列包括98名绝经后妇女 (30名关节骨折,68名选择性关节置换).
  • 排除标准包括影响骨密度的疾病或药物.
  • 主要测量的是25-氧维生素D和副甲状腺激素水平.

主要成果:

  • 与非骨质疏松症和骨质疏松症选择性关节置换组相比,患有骨骨折的女性的25-氧维生素D水平显著降低.
  • 与两组对照组相比,骨骨折的女性的副甲状腺激素水平显著更高.
  • 50%的部骨折的女性缺乏维生素D水平 (<或=30.0nmol/L).

结论:

  • 绝经后患有部骨折的女性经常表现出未被诊断的维生素D缺乏症.

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Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
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Cantilever Bending of Murine Femoral Necks

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  • 维生素D补充和副甲状腺激素抑制可能会降低未来骨折的风险并有助于愈合.
  • 提高对维生素D充足性的认识至关重要,尤其是在北度地区.