预测先进的近端结肠瘤与查西格莫多斯科比
T R Levin1, A Palitz, S Grossman
1Division of Research, Kaiser Permanente Medical Care Program, Oakland, Calif, USA. trl@itsa.ucsf.edu
JAMA
|May 11, 1999
概括
先进的近端瘤风险随着远端腺瘤组织学和65岁以上的年龄增加. 从50-55岁开始的西格莫视镜查和65岁后的结肠镜检查可能对预防结肠直肠癌有益.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 预防医学 预防医学
背景情况:
- 在查西格莫视镜检查后,对远端结肠管状腺瘤 (TAs) 进行后续结肠镜检查的指示还没有很好地定义.
- 识别患有近端结肠瘤风险较高的患者对于优化监测策略至关重要.
研究的目的:
- 为了调查远端腺瘤的特征 (大小,数量,状组织学),家族史和患者年龄是否预测了先进的近端结肠瘤.
- 为结直肠癌的个性化查和监测协议提供信息.
主要方法:
- 对2972名50岁以上无症状受试者进行结肠镜检查的截面分析.
- 从1994年至1995年间的西格莫视镜,结肠镜和病理学报告中收集的数据.
- 先进的近端瘤定义为腺癌或TA ≥1厘米,具有状特征,或近端结肠的严重发育不良.
主要成果:
- 晚期近端瘤的患病率在没有远端TAs,小TAs (<1厘米) 和大TAs (≥1厘米) 的组中相似.
- 患有远端小管状腺瘤或小状腺瘤的患者有12.1%的高级近端瘤的患病率.
- 远端管状腺瘤/状腺瘤 (OR 2.30),年龄≥65岁,多种腺瘤和积极的家族病史是先进近端瘤的显著预测因素;远端腺瘤的大小没有.
结论:
- 先进的近端瘤在有或没有远端TAS的个体中普遍存在.
- 晚期远端腺瘤组织学和65岁以上的人面临风险增加.
- 可能需要特定年龄的查方案,包括50-55岁时的西格莫视镜和65岁后的结肠镜检查.
更多相关视频
10:28Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
相关概念视频
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
