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Updated: Jul 17, 2026

Neo-Islet Formation in Liver of Diabetic Mice by Helper-dependent Adenoviral Vector-Mediated Gene Transfer
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Published on: October 10, 2012

在NOD小鼠中通过GAD表达或抑制β细胞来控制自身免疫糖尿病

J W Yoon1, C S Yoon, H W Lim

  • 1Laboratory of Viral and Immunopathogenesis of Diabetes, Julia McFarlane Diabetes Research Centre, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada. yoon@ucalgary.edu

Science (New York, N.Y.)
|May 15, 1999
PubMed
概括

胰腺β细胞中的谷氨酸脱碳酶 (GAD) 在NOD小鼠中驱动自身免疫糖尿病. 抑制GAD通过阻止T细胞生成来预防糖尿病,这表明GAD调制是1型糖尿病的潜在治疗方法.

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