第一个未受影响的怀孕使用状细胞贫血的植入前遗传诊断
1The Center for Reproductive Medicine and Infertility and the Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, New York, NY 10021, USA. zrosenw@mail.med.cornell.edu
JAMA
|May 18, 1999
概括
植入前遗传诊断 (PGD) 与体外受精 (IVF) 结合,成功使一对携带状细胞贫血的夫妇能够拥有未受影响的双胞胎. 这一突破为预防遗传疾病提供了希望.
科学领域:
- 生殖医学 生殖医学
- 人类遗传学 人类遗传学
- 胚胎学 胚胎学
背景情况:
- 状细胞贫血是一种普遍存在的自体相衰退性疾病.
- 之前对状细胞贫血的植入前遗传诊断 (PGD) 尝试并没有导致成功怀孕.
相关概念视频
02:45Blood Transfusion and Agglutination
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
01:22Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...