房节奏置用于预防阳性心房动
A M Gillis1, D G Wyse, S J Connolly
1Division of Cardiology, The University of Calgary, Calgary, Alberta, Canada. amgillis@ucalgary.ca
Circulation
|May 20, 1999
概括
在耐药PAF患者中,适应速率的心房节奏并没有预防心房动 (PAF). 这项研究发现,心房节拍对于预防复发的PAF发作没有短期益处.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 动性心房动 (PAF) 是一种常见的心律失常.
- 耐药PAF患者通常需要先进的干预措施.
- 在管理PAF中心房节奏的作用正在调查中.
研究的目的:
- 测试适应性心房节奏能否防止PAF在患有频繁,抗药性发作的患者中复发.
- 为了评估心房节拍的有效性,与在经过切除后的环境中没有节拍相比.
主要方法:
- 一项随机对照试验,涉及97名患有抗心律失常药物耐药PAF的患者.
- 在AV结节切除之前,患者接受了心脏起器.
- 随机化为没有节拍或心房节拍适应性节拍在剥离后的10周内.
主要成果:
- 在节奏和非节奏组之间的PAF第一次复发的时间没有显著差异 (P=NS).
- 在意向治疗分析 (P=0.08) 中,心房节拍并没有显著减少PAF负担.
- 一个配对的交叉分析表明,更短的PAF-free间隔和增加的PAF负担与心房节奏 (P<0.016).
结论:
- 适应心房率的节奏并不能防止药物耐药PAF患者的短期PAF复发,而没有症状的胸肌梗塞.
- 这些发现表明,心房节奏可能没有好处,可能会增加PAF负担在这个患者群体.
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