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Updated: Jul 21, 2026

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Infant Auditory Processing and Event-related Brain Oscillations
Published on: July 1, 2015
在出生非常早的青少年中,大脑结构和神经认知和行为功能
A L Stewart1, L Rifkin, P N Amess
1Department of Paediatrics, Rayne Institute, University College London Medical School, UK. ann@arlingtonave.demon.co.uk
Lancet (London, England)
|May 21, 1999
概括
非常早产会增加青春期的神经认知和行为问题. 磁共振成像 (MRI) 揭示了这些人的脑部异常比以前通过超声波检测的更多.
科学领域:
- 神经科学是一个神经科学.
- 发育儿科 发育儿科
- 放射学 放射学是指放射学
背景情况:
- 非常早产 (<33周) 的婴儿面临神经认知缺陷的更高风险.
- 新生儿超声波预测到8岁的神经发育结果,但以后的功能仍然不太了解.
- 这项研究研究了非常早产对青少年大脑结构和功能的长期影响.
研究的目的:
- 为了研究非常早产对青少年大脑结构的影响.
- 评估非常早产的青少年的神经认知和行为功能.
- 为了将青少年大脑的发现与早期生活因素和结果相关联.
主要方法:
- 一组105名在妊娠33周之前出生的婴儿被前性跟踪.
- 在14-15岁时,72名非常早产的个体和21名对照人接受了脑部MRI和神经认知/行为评估.
- 核磁共振扫描被神经放射学家独立审查.
主要成果:
- 超过一半 (40/72) 的非常早产的个体有异常的MRI扫描,相比一个控制.
- 常见的MRI异常包括心室,体和白质病变.
- 非常早产的个体表现出明显更多的阅读,调整和神经障碍,其行为与MRI发现有关.
结论:
- 非常早产的青少年表现出神经认知和行为问题的更高患病率.
- 超过一半的非常早产的个体在青少年MRI上表现出异常的大脑结构.
- 磁力共振成像对于在非常早产的个体中识别大脑异常至关重要,影响长期功能.
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