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在RPTP LAR的双联酸酶域的晶体结构

H J Nam1, F Poy, N X Krueger

  • 1Dana-Farber Cancer Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Cell
|May 25, 1999
PubMed
概括

人类RPTPLAR的蛋白氨酸酸酶 (PTP) D2域中的突变使催化活性成为可能. 这一发现挑战了以前的 PTPase 功能和域定向模型.

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