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相关概念视频

Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Pain01:20

Pain

Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...

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相关实验视频

Updated: Jun 26, 2026

Determining heat and mechanical pain threshold in inflamed skin of human subjects
13:21

Determining heat and mechanical pain threshold in inflamed skin of human subjects

Published on: January 14, 2009

剧烈的疼痛是一种急性疼痛.

D B Carr1, L C Goudas

  • 1Department of Anesthesia and Medicine, Tufts University School of Medicine, New England Medical Center, Boston, MA 02111, USA. dcarr02@emerald.tufts.edu

Lancet (London, England)
|June 22, 1999
PubMed
概括
此摘要是机器生成的。

有效的急性疼痛管理对于患者的康复和预防慢性疼痛至关重要. 改进的止痛策略,包括药理和非药理方法,在手术后是必不可少的.

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相关实验视频

Last Updated: Jun 26, 2026

Determining heat and mechanical pain threshold in inflamed skin of human subjects
13:21

Determining heat and mechanical pain threshold in inflamed skin of human subjects

Published on: January 14, 2009

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
07:12

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Published on: January 21, 2020

Characteristics of Pain Changes in Rats with Nerve Injury Within 24 hours After One-Time Tuina Intervention
05:24

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科学领域:

  • 麻醉学 麻醉学
  • 疼痛管理 疼痛管理
  • 神经外科 神经外科

背景情况:

  • 从历史上看,术后疼痛管理涉及延迟止痛药的使用,导致患者遭受重大痛苦.
  • 近一半的手术患者经历中度至严重的急性疼痛,影响恢复和增加并发症风险.

研究的目的:

  • 描述急性疼痛的过程.
  • 概述使用药理和非药理干预措施控制急性疼痛的措施.

主要方法:

  • 对麻醉后护理当前实践的审查.
  • 讨论基于药物和非药物治疗的疼痛管理策略.

主要成果:

  • 不充分的急性疼痛控制可以延长住院时间,并导致诸如肺炎等并发症.
  • 急性疼痛会导致长期的神经元变化,导致慢性疼痛和心理困扰.

结论:

  • 先进的急性疼痛控制对于患者的治疗结果和降低医疗保健成本至关重要.
  • 急性疼痛和其他类型的疼痛之间存在相似之处,这表明统一的管理方法.