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Updated: Jul 26, 2026

Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors
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通过HCV E2蛋白抑制干扰素诱导蛋白激酶PKR

D R Taylor1, S T Shi, P R Romano

  • 1Department of Molecular Microbiology and Immunology and Howard Hughes Medical Institute, University of Southern California, School of Medicine, Los Angeles, CA 90089, USA.

Science (New York, N.Y.)
|July 3, 1999
PubMed
概括

肝炎C病毒 (HCV) E2蛋白通过抑制PKR激酶来阻断干扰素的抗病毒作用. 这种相互作用解释了HCV如何逃避干扰素治疗,为治疗耐药性提供了洞察力.

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