在患有慢性左心室缺血功能障碍的患者中,心肌缺血和活力的预后值
A Pasquet1, A Robert, A M D'Hondt
1Divisions of Cardiology and Nuclear Medicine, University of Louvain Medical School, Brussels, Belgium.
Circulation
|July 14, 1999
概括
塔光学和多布他胺回声心脏学识别缺血性或可活性心肌,预测左心室功能障碍患者的复血管化后的生存率. 这些测试有助于选择患者以改善心脏结果.
科学领域:
- 心脏病学 心脏病学
- 核心脏病学 核心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 在左心室 (LV) 功能障碍中,和多布他胺回声心脏成像预测左心室 (LV) 功能障碍的复苏后的收缩性恢复.
- 这些用于预测结果的非侵入性方法的预测影响仍然不确定.
研究的目的:
- 评估在患有冠状动脉疾病和 LV 功能障碍的患者中,他光学和多布他胺心声学的预后影响.
- 为了确定确定缺血性心肌或可活性心肌是否会影响重血管化后的长期存活.
主要方法:
- 对137名冠心病和LV功能障碍患者的前性研究.
- 炼-再分配-再注射的素光学和多布他胺心电回声学,用于评估心肌缺血和活力.
- 患者接受了再血管化 (n=94) 或医疗治疗 (n=43),在平均33个月的随访期间,心脏死亡率是主要终点.
主要成果:
- 长期存活与冠状动脉疾病的程度,糖尿病,治疗类型,缺血性心肌 () 和可活性心肌 (两种测试) 相关.
- 在经过再血管化的缺血性或可活性心肌患者中,三年生存率显著更高.
- 在所有患有三血管或左主血管疾病的患者中,重血管化改善了生存率,特别是那些患有已确定的缺血或可活性心肌的患者.
结论:
- 缺血性心肌 (光学) 和可活性心肌 (多布他胺心声学) 是LV缺血性功能障碍中死亡率的独立预测因素.
- 这些发现可以帮助在术前选择患者进行复血管化手术.
- 非侵入性成像模式在冠状动脉疾病的风险分层和治疗计划中起着至关重要的作用.
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