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在"白袍"效应期间,肌肉和皮肤交感神经流动
1Cattedra di Medicina Interna, Università di Milano, Ospedale S. Gerardo, Monza, and Centro di Fisiologia Clinica e Ipertensione, IRCCS, Milano, Italy.
Circulation
|July 21, 1999
概括
在血压测量期间的"白袍"效应会增加血压和心率. 这种反应涉及肌肉交感神经活动的减少和皮肤交感神经活动的增加.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统研究 自主神经系统研究
背景情况:
- 压力计血压测量可以触发警报反应,提高血压和心率.
- 这种"白袍"效应对交感神经流量的影响仍然未被探索.
研究的目的:
- 为了研究"白衣"效应期间同情神经流量的变化.
- 为了确定肌肉和皮肤交感神经对血压测量引起的压力的特定反应.
主要方法:
- 微神经图用于测量10名轻度高血压患者的肌肉和皮肤交感神经活动.
- 使用Finapres和ECG分别监测了动脉血压和心率.
- 测量是在对照期,医生检查血压测量和恢复期进行的.
主要成果:
- 医生的访问导致皮肤交感神经流量的显著增加 (+38.6%).
- 相反,肌肉交感神经流量显著下降 (-25.5%).
- 这些变化在访问期间持续存在,之后逐渐得到解决.
结论:
- 对血压测量的警报反应引起了不同的同情反应:皮肤中的同情刺激和肌肉中的同情抑制.
- 这种差异性上腺神经系统行为是"白袍"现象的特征.
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