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在患有因大动脉狭窄而导致压力过重的患者中,心肌局部运动模式的改变
M Stuber1, M B Scheidegger, S E Fischer
1Institute of Biomedical Engineering, University and ETH Zurich Department of Internal Medicine, Zurich, Switzerland.
Circulation
|July 27, 1999
概括
与健康的个人和运动员相比,患有大动脉狭窄症的患者表现出心脏扭曲的增加和延长的透气解. 这种心肌运动的变化可能会导致心脏静脉功能障碍.
科学领域:
- 心血管成像 - 心血管成像
- 心脏机械学心脏机械学
- 心肌运动分析
背景情况:
- 磁共振 (MR) 组织标记非侵入性地评估左心室运动.
- 心脏扭转和透气放松对于心脏功能至关重要.
- 之前的研究已经在各种心脏疾病中探索了这些参数.
研究的目的:
- 为了研究左心室扭转和大动脉狭窄患者的舒缓性放松的变化.
- 为了将这些参数与健康的对照组和表现出生理性缩的运动员进行比较.
- 评估MR组织标记在压力过载条件下的诊断潜力.
主要方法:
- 利用一种新的心脏固态运动跟踪 (CSPAMM) 标记技术进行详细的静缩和静缩运动分析.
- 检查了12名大动脉狭窄患者,11名健康对照患者和11名精英划船员的基底和顶点水平的心肌运动.
- 量化了心扭转和腹扭转模式.
主要成果:
- 健康的个体表现出一种特征性的缩扭转运动,与反时钟针方向的顶点旋转和时钟针方向的底部旋转.
- 与对照人群相比,运动员表现出不变的扭转和解.
- 大动脉狭窄患者显著增加了缩扭曲和延长了腹转缩角扭曲.
结论:
- 在压力过载的心脏中观察到的扭曲行为与理论预测一致.
- 在大动脉狭窄患者中延迟的扩张性解扭可能表明对扩张性功能障碍的倾向.
- 磁力共振成像组织标记为疾病状态中的心脏力学提供了宝贵的见解.
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