在人体模拟腹腔动脉短心期间,对同情活动的反射控制
M L Smith1, J A Joglar, S L Wasmund
1Department of Integrative Physiology, University of North Texas Health Science Center, Ft Worth, Texas, USA. msmith@hsc.unt.edu
Circulation
|August 10, 1999
概括
动脉气质受体主要控制在人体内心室动脉节律失常期间的交感神经活动 (SNA). 心肺气质受体也起着作用,为同情反应提供抑制调节.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统调节自主神经系统调节
- 巴罗受体的功能
背景情况:
- 腹腔动脉节律失常症独特地刺激着巴罗受体.
- 对人类交感神经活动 (SNA) 的影响尚未完全理解.
- 调查在心律失常期间自主控制中的巴罗受体作用至关重要.
研究的目的:
- 为了确定心肺和动脉巴罗受体的相对贡献.
- 为了了解他们对SNA和动脉压的控制在心室节拍过程中.
- 为了阐明心律失常期间的自主反应.
主要方法:
- 在心室节拍和酸注射期间比较SNA和血液动力学反应.
- 使用头向上倾斜和烯酸来隔离巴罗受体刺激.
- 在受控条件下分析了SNA和动脉压的关系.
主要成果:
- 动脉巴罗反射控制在尼托普鲁塞德输注期间比心室节奏更为主导.
- 当动脉压在节拍过程中正常化时,SNA下降.
- 在节奏时使心脏填充压力正常化导致SNA增加更大.
结论:
- 动脉巴罗反射主要介于人类心室动脉节律失常症中的同情激发.
- 心肺气质受体提供显著的SNA的抑制调节.
- 这些发现澄清了巴罗受体对心律失常期间自主控制的影响.
关键词:
非编程性的非编程性.相关概念视频
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