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Updated: Jul 11, 2026

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一种SMAD泛基因酶准了BMP通路,并影响了胚胎模式形成

H Zhu1, P Kavsak, S Abdollah

  • 1Department of Biochemistry and Cell Biology and Institute for Cell and Developmental Biology, State University of New York, Stony Brook 11794-5215, USA.

Nature
|August 24, 1999
PubMed
概括

Smurf1,一种E3泛基因酶,针对特定的SMAD蛋白进行降解,控制骨形态遗传蛋白 (BMP) 信号传递和胚胎发育. 这种机制通过调节TGF-β超家族通路来调节细胞生长和分化.

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