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Updated: Aug 10, 2026

Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
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双缺小小鼠对Fas诱导的肝细胞亡有抗性

X M Yin1, K Wang, A Gross

  • 1Department of Pathology, Washington University School of Medicine, Howard Hughes Medical Institute, St Louis, Missouri 63110, USA.

Nature
|September 7, 1999
PubMed
概括

缺乏Bid蛋白的小鼠在Fas抗体注射后幸存下来,与野生型小鼠不同. 比德缺陷阻止了线粒体细胞染色体c的释放,这对亡信号传递至关重要.

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