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通过与Gαα相关联的rap1GAP异型激活ERK/MAPK通路 (i)

N Mochizuki1, Y Ohba, E Kiyokawa

  • 1Department of Pathology, Research Institute, International Medical Center of Japan, Tokyo.

Nature
|September 7, 1999
PubMed
概括

通过招募rap1GAPII,G (i) 蛋白的α子单元激活了ERK/MAPK通路. 这降低了与GTP结合的Rap1,从而激活了Ras-ERK/MAPK的线索.

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