蛋白质性费洛蒙影响陆地的雌性受体
S M Rollmann1, L D Houck, R C Feldhoff
1Department of Ecology and Evolution, University of Chicago, 1101 East 57 Street, Chicago, IL 60637, USA. Department of Zoology, Oregon State University, 3029 Cordley Hall, Corvallis, OR 97331, USA. smrollma@midway.uchicago.edu
概括
研究人员在雄性 salamanders 中发现了一种蛋白质,plethodontid受体因子 (PRF),在求爱期间增加了雌性受体. 这个费洛蒙.
科学领域:
- * 动物学 动物学
- * 动物行为
- * 分子生物学 * 分子生物学
背景情况:
- *雄性陆地拥有下下腺,产生信号分子.
- *女性的受体性对于许多物种成功繁殖至关重要,包括Plethodon jordani.
研究的目的:
- * 为了隔离和描述来自男性Plethodon jordani下腺的蛋白质性费洛蒙.
- * 确定这种费洛蒙在女性生殖行为中的功能.
- * 调查费洛蒙的分子基础和进化影响.
主要方法:
- *从雄性的腺体中分离和净化一个22千多的蛋白质.
- *在求爱期间向雌性提供纯化蛋白质的实验,以评估行为变化.
- * 分子分析包括cDNA转录,克隆,测序和同质性搜索.
主要成果:
- * 一种叫做斑牙受体因子 (PRF) 的蛋白质被分离和鉴定出来.
- * 在实验性地使用时,PRF显著增加了女性的受体性.
- *PRF表现出对细胞因子的同质性,特别是交白素-6家族,这表明这种蛋白质类的新功能.
结论:
- * Plethodontid受体因子 (PRF) 作为一种费罗蒙,可以增强Plethodon jordani的雌性受体.
- * 这一发现揭示了前所未知的细胞因子在动物沟通和繁殖中的作用.
- *这项研究提供了关于两动物生殖信号的演变的见解.
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