在马尔凡综合征的表型评估中,持续性抽的重要性
R Fattori1, C A Nienaber, B Descovich
1Institute of Radiology, University Hospital S Orsola, Bologna, Italy. ross@med.unibo.it
Lancet (London, England)
|September 18, 1999
概括
长期抽,脊柱状况,在马方综合征患者中非常普遍,影响了92%的研究对象. 这种特征标志甚至在年轻人身上也存在,有助于早期诊断马方综合征.
科学领域:
- 医学成像医学成像
- 遗传学 是一个遗传学.
- 心脏病学 心脏病学
背景情况:
- 由于各种症状,诊断马方综合征是具有挑战性的.
- 早期识别对于预防大动脉并发症至关重要.
- 马尔凡综合征中长期抽的患病率和诊断效用尚不清楚.
研究的目的:
- 为了确定在马尔凡综合征中持续性抽的患病率.
- 为了研究持续性抽出症和大动脉病理之间的关系.
- 为了评估长期抽作为马方综合征的诊断标志物.
主要方法:
- 在83名马凡综合征患者中对大动脉和脊椎进行磁共振成像 (MRI).
- 评估持续性抽和大动脉干扰.
- 与100名接受腰椎MRI的对照人群进行比较.
主要成果:
- 在92%的马方综合征患者中发现了持续性抽,而对照组中为0%.
- 持续性抽的严重程度与年龄相关.
- 在大动脉扩张和持续性抽血之间没有观察到任何关联.
结论:
- 持续性抽是马方综合征的高度流行和特征性症状.
- 它的存在甚至在儿科患者中也是有迹象的.
- 持续性抽是马尔凡综合征的一个有价值的诊断标准.
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