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在抑制Otx2和定位中/后脑组织者的Gbx2的作用

S Millet1, K Campbell, D J Epstein

  • 1Developmental Genetics Program and Howard Hughes Medical Institute, Skirball Institute of Biomolecular Medicine, New York, New York 10016, USA.

Nature
|September 18, 1999
PubMed
概括

基因Gbx2对于小鼠中/后脑 (MHB) 组织者的定位至关重要. 它的缺失导致Otx2域扩张,扰乱MHB的发展,导致大脑结构的改变.

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