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Updated: Jul 10, 2026

Assessing the Development of Murine Plasmacytoid Dendritic Cells in Peyer's Patches Using Adoptive Transfer of Hematopoietic Progenitors
13:34

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Published on: March 17, 2014

对于小鼠淋巴系统的发展,需要Prox1功能

J T Wigle1, G Oliver

  • 1Department of Genetics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

Cell
|September 28, 1999
PubMed
概括

Prox1是一种关键基因,对淋巴系统发育至关重要. 在小鼠中缺少它会阻止淋巴细胞的芽和发芽,这表明血管和淋巴系统的独立发展.

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Development of the Lymphatic System01:15

Development of the Lymphatic System

The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...