相关实验视频

Updated: Jul 19, 2026

Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement
08:36

Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement

Published on: September 6, 2011

在基于表型的屏幕中确定了线粒状双极性的小分子抑制剂

T U Mayer1, T M Kapoor, S J Haggarty

  • 1Department of Cell Biology, and Institute of Chemistry and Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Thomas_Mayer@hms.harvard.edu

Science (New York, N.Y.)
|November 5, 1999
PubMed
概括

莫纳斯托尔是一种新型的小分子,通过抑制线粒激素Eg5运动蛋白质来阻止哺乳动物细胞在线粒分裂的过程,这对于双极性至关重要. 这一发现为研究细胞分裂机制提供了新的工具.

更多相关视频

Spatial Separation of Molecular Conformers and Clusters10:37

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

Multimodal Nonlinear Hyperspectral Chemical Imaging Using Line-Scanning Vibrational Sum-Frequency Generation Microscopy08:49

Multimodal Nonlinear Hyperspectral Chemical Imaging Using Line-Scanning Vibrational Sum-Frequency Generation Microscopy

Published on: December 1, 2023

相关概念视频

Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...