通过不同的机制,通过chk1和rad53蛋白激酶控制DNA损伤检查点

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Updated: Jul 15, 2026

Study of the DNA Damage Checkpoint using Xenopus Egg Extracts
10:55

Study of the DNA Damage Checkpoint using Xenopus Egg Extracts

Published on: November 5, 2012

Y Sanchez1, J Bachant, H Wang

  • 1Howard Hughes Medical Institute, Verna and Marrs McLean Department of Biochemistry, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

Science (New York, N.Y.)
|November 5, 1999
PubMed
概括

在Saccharomyces cerevisiae中,Chk1和Rad53激酶防止DNA损伤后的细胞分裂. 它们以并行途径起作用,维持酶抑制剂和调节关键蛋白质,确保细胞存活.

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