用卡蒂尔-爱德华兹和佩里卡本心周假体进行大动脉置换后的中期比较随访
T Le Tourneau1, C Savoye, E P McFadden
1Service de Chirurgie Cardio-Vasculaire B, Hôpital Cardiologique, Lille, France. goleklunder@chru.lille.fr
Circulation
|November 24, 1999
概括
第二代Pericarbon心周门在甲状腺门更换8年后,与Carpentier-Edwards门相比,其结构性故障和重新运行率更高. 这表明大动脉门手术中佩里碳假肢的长期结果较差.
科学领域:
- 心脏外科手术 心脏外科手术
- 生物材料科学 生物材料科学
- 假肢技术 假肢技术
背景情况:
- 第一代心周膜表现出高率的过早恶化.
- 这项研究解决了对假体心脏门的长期耐用性改善的需求.
研究的目的:
- 通过使用两种类型的第二代心周假肢来比较主动脉置换的临床结果:Pericarbon和Carpentier-Edwards.
- 评估这些心周膜的长期性能和耐用性.
主要方法:
- 一组162名患者在1987年至1994年间接受了大动脉置换,其中81人接受了Pericarbon和81人接受了Carpentier-Edwards假肢.
- 佩里碳门的平均随访时间为4.4年,卡蒂尔-爱德华兹门的平均随访时间为4.8年,总共为745个患者年.
- 评估的结果包括死亡率,存活率,血栓栓塞,结构失效率和重新操作率.
主要成果:
- 在8年后,二氧化碳门的结构性故障率显著提高 (76.9%的无故障率与卡蒂尔-爱德华兹的100%相比,P<0.01) 和重新操作 (7.4%与0%).
- 碳结构故障主要与化和狭窄有关.
- 在Carpentier-Edwards组中没有观察到结构门故障或重新启动.
结论:
- 与Carpentier-Edwards假体相比,心膜假体显示出不良的结果,大动脉置换后八年.
- 结构门故障的高发病率和需要重新操作的需要在Pericarbon门中被注意到.
- 在这个患者群体中,Carpentier-Edwards 假肢表现出优越的耐用性和性能.
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