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Updated: Jan 30, 2026

Measuring Protein Binding to F-actin by Co-sedimentation
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在小鼠中,神经管形态发生需要含有PDZ域的活性蛋白Shroom

J D Hildebrand1, P Soriano

  • 1Program in Developmental Biology and Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.

Cell
|December 10, 1999
PubMed
概括

在小鼠中发生的一种新型基因突变,称为shroom (shrm),破坏神经管的闭合,导致出生缺陷. 在胚胎发育过程中,Shrm蛋白对细胞结构和细胞骨调节至关重要.

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